pitmanme.github.io

repository for M. E. Pitman of UCI formerly UMD/NIH

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pitmanme.github.io

Access lecture notes for 02/28/2022 here: https://github.com/pitmanme/pitmanme.github.io/blob/master/phrmsci_275_lecture/phrmsci_275_lecture_proteins.pptx

In development:

The system_builder package can be accessed here.

The code for publications:

  1. Intrinsic elasticity of nucleosomes is encoded by histone variants and calibrated by their binding partners, PNAS
  2. Minimal Cylinder Analysis Reveals the Mechanical Properties of Oncogenic Nucleosomes, Biophysical Journal

Minimal Cylinder Analysis Workflow image

Link to the code for Young’s modulus calculation

Link to scripts for nucleosome variants, variables hardcoded